Caenorhabditis Elegans has been a popular model organism for biological research for over thirty years and has been used to investigate many aspects of animal development, for example apoptosis, the Hox genes, signal transduction pathways, and the development of the nervous system. It has
recently taken on new importance with the publication of its entire genome sequence in 1998. This book contains all the basic information on C. elegans required to use it: it's natural history, anatomy, life cycle, development, and evolution; information on how to obtain, grow, and maintain C.
elegans for use as a model system; the genome project and how to use genome sequence information by searching the database for homologues using different search methods and then how to analyse the search data; the essential practical details of transformation and common uses for the technique; and
how to analyse phenotype by microscopy, including Normaski, fluorescence, 4-dimensional, and electron... [More...] [Edit review] [Delete review]